Bevirimat (Synonyms: 3-O-(3',3'-Dimethylsuccinyl) Betulinic Acid, Bevirimat, FH11327, MPC-4326) |
| Catalog No.GC35508 |
An inhibitor of HIV-1 virion maturation
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 174022-42-5
Sample solution is provided at 25 µL, 10mM.
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Bevirimat (PA-457; MPC-4326; YK FH312) is an anti-HIV drug derived from a betulinic acid-like compound; is believed to inhibit HIV by a novel mechanism, so-called maturation inhibition.
[1]. Smith PF, et al. Phase I and II study of the safety, virologic effect, and pharmacokinetics/pharmacodynamics of single-dose 3-o-(3',3'-dimethylsuccinyl)betulinic acid (bevirimat) against human immunodeficiency virus infection. Antimicrob Agents Chemother. 2007 Oct;51(10):3574-81. [2]. Salzwedel K, et al. Maturation inhibitors: a new therapeutic class targets the virus structure. AIDS Rev. 2007 Jul-Sep;9(3):162-72. [3]. Martin DE, et al. Bevirimat: a novel maturation inhibitor for the treatment of HIV-1 infection. Antivir Chem Chemother. 2008;19(3):107-13.
Average Rating: 5 (Based on Reviews and 14 reference(s) in Google Scholar.)
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