cGAMP disodium (Synonyms: Cyclic GMP-AMP disodium; 3',3'-cGAMP disodium) |
Catalog No.GC62241 |
cGAMP (Cyclic GMP-AMPP) disodium functions as an endogenous second messenger in metazoans and triggers interferon production in response to cytosolic DNA.
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Cas No.: 2407516-83-8
Sample solution is provided at 25 µL, 10mM.
cGAMP disodium (Cyclic GMP-AMP disodium) is the third cyclic dinucleotide (CDN) to be discovered in bacteria. cGAMP disodium is an effective adjuvant for sublingual vaccination capable of promoting broad immunity including serum anti-PA neutralizing and anti-PA SIgA responses in airway secretions[1][2].
[1]. Wright TA, et al. Second messengers and divergent HD-GYP phosphodiesterases regulate 3’,3’-cGAMP signaling. Mol Microbiol. 2020;113(1):222-236.
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