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Chalcone

Catalog No.GC63826 Copy One-Click Copy Product Info

Chalcone is isolated from Glycyrrhizae inflata and used to synthesize chalcone derivatives.

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Chalcone Chemical Structure

Cas No.: 94-41-7

Size Price Stock Qty
50mg
$7.00
In stock
100mg
$11.00
In stock

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Sample solution is provided at 25 µL, 10mM.



Description of Chalcone

Chalcone is isolated from Glycyrrhizae inflata and used to synthesize chalcone derivatives. Chalcone derivatives possess varied biological and pharmacological activity, including anti-inflammatory, antioxidative, antibacterial, anticancer, and anti-parasitic activities[1].

Chalcone derivatives are synthesized by Claisen-Shimidt base-catalyzed condensation of appropriate aromatic ketones or substituted aromatic ketones with benzaldehydes or substituted benzaldehydes[1].

[1]. Shailendra Mandge,et al. Synthesis and Characterization of Some Chalcone Derivatives. Trends in Applied Sciences Research Volume 2 (1): 52-56, 2007

Chemical Properties of Chalcone

Cas No. 94-41-7 SDF
Formula C15H12O M.Wt 208.26
Solubility DMSO : 100 mg/mL (480.17 mM; Need ultrasonic) Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Chalcone

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 4.8017 mL 24.0085 mL 48.0169 mL
5 mM 960.3 μL 4.8017 mL 9.6034 mL
10 mM 480.2 μL 2.4008 mL 4.8017 mL
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**When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / CoA (available online).

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In vivo Formulation Calculator (Clear solution) of Chalcone

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

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Reviews

Review for Chalcone

Average Rating: 5 ★★★★★ (Based on Reviews and 37 reference(s) in Google Scholar.)

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