DFP00173 |
| Catalog No.GC38769 |
DFP00173 is a potent and selective aquaporin-3 (AQP3) inhibitor.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 672286-03-2
Sample solution is provided at 25 µL, 10mM.
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DFP00173 is a potent and selective aquaporin-3 (AQP3) inhibitor. DFP00173 inhibits mouse and human AQP3 with an IC50 of ∼0.1-0.4 μM. DFP00173 is selective for AQP3 over the homologous AQP isoforms AQP7 and AQP9[1].
DFP00173 inhibits the glycerol permeability of human erythrocytes with an IC50 of ~0.2 µM[1].
[1]. Sonntag Y, et al. Identification and characterization of potent and selective aquaporin-3 and aquaporin-7 inhibitors. J Biol Chem. 2019 May 3;294(18):7377-7387.
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