Dithranol (Anthralin) (Synonyms: 1,8,9-Anthracenetriol, Dithranol, NSC 43970, NSC 629313) |
| Catalog No.GC31684 |
Dithranol (Anthralin) (Anthralin) is an anthraquinone derivative, with potent anti-psoriatic effects.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1143-38-0
Sample solution is provided at 25 µL, 10mM.
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Dithranol is highly effective in the treatment of psoriasis.Target: OthersDithranol accumulates in mitochondria where it interferes with the supply of energy to the cell, probably by the oxidation of dithranol releasing free radicals. This impedes DNA replication and so slows the excessive cell division that occurs in psoriatic plaques. In addition Dithranol may act by reducing the elevated levels of cGMP that occurs in psoriasis.
[1]. http://en.wikipedia.org/wiki/Dithranol
Average Rating: 5 (Based on Reviews and 38 reference(s) in Google Scholar.)
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