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DTG Catalog No.GC16598

sigma receptor agonist

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1g
$64.00
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Sample solution is provided at 25 µL, 10mM.

Quality Control

Quality Control & SDS

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Chemical Properties

Cas No. 97-39-2 SDF
Chemical Name (E)-1,2-di-o-tolylguanidine
Canonical SMILES N/C(NC1=CC=CC=C1C)=N\C2=CC=CC=C2C
Formula C15H17N3 M.Wt 239.32
Solubility <5.98mg/ml in DMSO; <5.98mg/ml in ethanol Storage Store at RT
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
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Background

Ditolylguanidine (1,3-Di-o-tolylguanidine) is an agonist of sigma receptor (σ1/σ2 receptor)[1].

References:
[1]. Skuza G, et al. Sigma1 receptor antagonists attenuate antidepressant-like effect induced by co-administration of 1,3 di-o-tolylguanidine (DTG) and memantine in the forced swimming test in rats. Pol J Pharmacol. 2003 Nov-Dec;55(6):1149-52.