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Dyphylline Catalog No.GC13652

Pan-PDE inhibitor

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10mM (in 1mL DMSO)
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In stock

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Sample solution is provided at 25 µL, 10mM.

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Chemical Properties

Cas No. 479-18-5 SDF
Chemical Name 7-(2,3-dihydroxypropyl)-1,3-dimethylpurine-2,6-dione
Canonical SMILES CN1C2=C(C(=O)N(C1=O)C)N(C=N2)CC(CO)O
Formula C10H14N4O4 M.Wt 254.24
Solubility ≥ 7.8 mg/mL in DMSO, ≥ 21.96 mg/mL in EtOH with ultrasonic and warming, ≥ 17.17 mg/mL in H2O Storage Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
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**When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / CoA (available online).



Dyphylline acts as an adenosine receptor antagonist and phosphodiesterase inhibitor, which is used in the treatment of respiratory disorders.Target: Adenosine Receptor; PDEDyphylline (trade names Dilor, Lufyllin), also known as diprophylline, is a xanthine derivative with bronchodilator and vasodilator effects. It is used in the treatment of respiratory disorders like asthma, cardiac dyspnea, and bronchitis. It acts as an adenosine receptor antagonist and phosphodiesterase inhibitor.

[1]. Schwabe U, et al. Xanthine derivatives as antagonists at A1 and A2 adenosine receptors. Naunyn Schmiedebergs Arch Pharmacol. 1985 Sep;330(3):212-21.
[2]. Iancu L, et al. Trials with xanthine derivatives in systemic treatment of psoriasis. Dermatologica. 1979;159(1):55-61.