EACC |
Catalog No.GC39305 |
EACC is a reversible autophagy inhibitor, which can block autophagic flux.
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Cas No.: 864941-31-1
Sample solution is provided at 25 µL, 10mM.
EACC is a reversible autophagy inhibitor, which can block autophagic flux. EACC selectively inhibits the translocation of autophagosome-specific SNARE Stx17 thereby blocking autophagosome-lysosome fusion[1].
[1]. Vats S, et al. A reversible autophagy inhibitor blocks autophagosome-lysosome fusion by preventing Stx17 loading onto autophagosomes. Mol Biol Cell. 2019 Aug 1;30(17):2283-2295.
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