Etoxazole |
Catalog No.GC47326
One-Click Copy Product Info
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An organofluorine acaricide
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 153233-91-1
Sample solution is provided at 25 µL, 10mM.
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Etoxazole is an organofluorine acaricide.1,2 It induces toxicity in two-spotted spider mite (T. urticae) larvae (LC50 = 0.036 mg/L for the London reference strain) through inhibition of chitin synthase 1. It reduces acetylcholinesterase (AChE) activity in the freshwater fish O. niloticus in a concentration-dependent manner.3 Etoxazole (2.2-22 mg/kg per day) inhibits the activity of catalase, glutathione peroxidase (GPX), and AChE in the liver and kidneys of rats in a dose-dependent manner.2 Formulations containing etoxazole have been used for the control of mites in agriculture.
1.Demaeght, P., Osborne, E.J., Odman-Maresh, J., et al.High resolution genetic mapping uncovers chitin synthase-1 as the target-site of the structurally diverse mite growth inhibitors clofentezine, hexythiazox and etoxazole in Tetranychus urticaeInsect Biochem. Mol. Biol.5152-61(2014) 2.Yilmaz, M., Rencuzogullari, E., and Canli, M.Investigations on the effects of etoxazole in the liver and kidney of Wistar ratsEnviron. Sci. Pollut. Res. Int.24(24)19635-19639(2017) 3.Sevgiler, Y., OruÇ, E.O., and Üner, N.Evaluation of etoxazole toxicity in the liver of Oreochromis niloticusPestic. Biochem. Physiol.78(1)1-8(2004)
| Cas No. | 153233-91-1 | SDF | |
| Canonical SMILES | CC(C)(C)C1=CC=C(C2N=C(C3=C(F)C=CC=C3F)OC2)C(OCC)=C1 | ||
| Formula | C21H23F2NO2 | M.Wt | 359.4 |
| Solubility | Chloroform: Slightly Soluble | Storage | Store at -20°C |
| General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
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| Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. | ||
| Prepare stock solution | |||
|
1 mg | 5 mg | 10 mg |
| 1 mM | 2.7824 mL | 13.9121 mL | 27.8242 mL |
| 5 mM | 556.5 μL | 2.7824 mL | 5.5648 mL |
| 10 mM | 278.2 μL | 1.3912 mL | 2.7824 mL |
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
g
μL
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Quality Control & SDS
- View current batch:
- Purity: >98.00% Appearance: A solid
- COA (Certificate of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Average Rating: 5 (Based on Reviews and 36 reference(s) in Google Scholar.)