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Euphol Acetate

Catalog No.GC46145

A triterpenoid with diverse biological activities

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Euphol Acetate Chemical Structure

Cas No.: 13879-04-4

Size Price Stock Qty
1mg
$301.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Product Documents

Quality Control & SDS

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Background

Euphol acetate is a triterpenoid that has been found in Euphorbia species and has diverse biological activities.1,2,3 It reduces sodium fluorescein uptake by CHO cells expressing organic anion-transporting polypeptide 1B1 (OATP1B1) and OATP1B3 to 29.2 and 40.2% of controls, respectively, when used at a concentration of 10 μM.3 Euphol acetate (50 and 100 μg/ml) induces mortality in 40% of B. glabrata snails.2

|1. De Pascual Teresa, J., Urones, J.G., Marcos, I.S., et al. Triterpenes from Euphorbia broteri. Phytochemistry 26(6), 1767-1776 (1987).|2. Mata, R.C.S., de Mendon•a, I.M.D., Vieira, L., et al. Molluscicidal activity of compounds isolated from Euphorbia conspicua N. E. Br. J. Braz. Chem. Soc. 22(10), 1880-1887 (2011).|3. De Bruyn, T., van Westen, G.J.P., Ijzerman, A.P., et al. Structure-based identification of OATP1B1/3 inhibitors. Mol. Pharmacol. 83(6), 1257-1267 (2013).

Chemical Properties

Cas No. 13879-04-4 SDF
Canonical SMILES C[C@H](CC/C=C(C)/C)[C@]1([H])CC[C@]([C@@]1(C)CC2)(C)C3=C2[C@]4(C)[C@](CC3)([H])C(C)(C)[C@@H](OC(C)=O)CC4
Formula C32H52O2 M.Wt 468.8
Solubility DMF: Soluble,DMSO: Soluble,Ethanol: Soluble,Methanol: Soluble Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

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1 mg 5 mg 10 mg
1 mM 2.1331 mL 10.6655 mL 21.3311 mL
5 mM 0.4266 mL 2.1331 mL 4.2662 mL
10 mM 0.2133 mL 1.0666 mL 2.1331 mL
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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Average Rating: 5 ★★★★★ (Based on Reviews and 31 reference(s) in Google Scholar.)

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