(Hyp⁴⁷⁴·⁴⁷⁷,Gln⁴⁷⁹)-cyclo-α-Fetoprotein (471-479) (human, lowland gorilla) |
Catalog No.GA20223 |
The cyclic α-fetoprotein-derived peptide analog efficiently inhibited the growth of estrogen-dependent MCF-7 human breast cancer cell xenografts. The extent of inhibition was similar to that of tamoxifen. In contrast to tamoxifen the peptide did not interfere with estrogen binding to its receptor and therefore further development of this compound might yield a new class of valuable agents for the effective treatment of breast cancer.
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Cas No.: 393827-70-8
Sample solution is provided at 25 µL, 10mM.
The cyclic α-fetoprotein-derived peptide analog efficiently inhibited the growth of estrogen-dependent MCF-7 human breast cancer cell xenografts. The extent of inhibition was similar to that of tamoxifen. In contrast to tamoxifen the peptide did n
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