BKI-1369 |
| Catalog No.GC35531 |
BKI-1369 is a bumped kinase inhibitor (BKI).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1951431-22-3
Sample solution is provided at 25 µL, 10mM.
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BKI-1369 is a bumped kinase inhibitor (BKI). BKI-1369 increases human Ether-a-go-go-related gene (hERG)-inhibitory activity with an IC50 of 1.52 μM. BKI-1369 reduces the parasite burden and diseases severity in the gnotobiotic pig model. BKI-1369 has been well characterized for potency, stability, metabolism, toxicity, pharmacokinetics and is potent against C. parvum in infected mice and calves[1]. IC50: 1.52 μM (hERG)[1]
[1]. Lee S, et al. Therapeutic Efficacy of Bumped Kinase Inhibitor 1369 in a Pig Model of Acute Diarrhea Caused by Cryptosporidium hominis. Antimicrob Agents Chemother. 2018 Jun 26;62(7).
Average Rating: 5 (Based on Reviews and 31 reference(s) in Google Scholar.)
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