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Heraclenin

Catalog No.GC36220

Heraclenin, a natural furanocoumarin, significantly inhibits T cell receptor-mediated proliferation in human primary T cells in a concentration-dependent manner by targeting nuclear factor of activated T-cells (NFAT).

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Heraclenin Chemical Structure

Cas No.: 2880-49-1

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Heraclenin, a natural furanocoumarin, isolated from the root parts of the plant Prangos pabularia. Heraclenin significantly inhibits T cell receptor-mediated proliferation in human primary T cells in a concentration-dependent manner by targeting nuclear factor of activated T-cells (NFAT)[1]. NFAT[1]

[1]. MÁrquez N, et al. Imperatorin inhibits T-cell proliferation by targeting the transcription factor NFAT. Planta Med. 2004 Nov;70(11):1016-21.

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