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Kasugamycin hydrochloride hydrate

Catalog No.GC36385 Copy One-Click Copy Product Info

Kasugamycin hydrochloride hydrate (Ksg hydrochloride hydrate) is an antibiotic which binds both the 30S and 70S ribosome but not isolated 50S subunits.

Products are for research use only. Not for human use. We do not sell to patients.

Kasugamycin hydrochloride hydrate Chemical Structure

Cas No.: 200132-83-8

Size Price Stock Qty
10mM (in 1mL Water)
$50.00
In stock
1g
$54.00
In stock

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Customer Reviews

Based on customer reviews.

Sample solution is provided at 25 µL, 10mM.



Description of Kasugamycin hydrochloride hydrate

Kasugamycin hydrochloride hydrate is an important amino-glycoside family antibiotic and widely used for veterinary and agricultural applications.

[1]. Chenchen Zhu, et al. Identification and engineering of regulation-related genestoward improved kasugamycin production. Appl Microbiol Biotechnol, DOI 10.1007/s00253-015-7082-3 [2]. Yoshii A, et al. Two types of genetic carrier, the IncP genomic island and the novel IncP-1β plasmid, for the aac(2')-IIa gene that confers kasugamycin resistance in Acidovorax avenae ssp. avenae. Mol Plant Pathol. 2015 Apr;16(3):288-300.

Chemical Properties of Kasugamycin hydrochloride hydrate

Cas No. 200132-83-8 SDF
Canonical SMILES OC(C(N[C@@H](C[C@@H]1N)[C@@H](C)O[C@]1([H])O[C@@H]2[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)[C@H]2O)=N)=O.[H]Cl.O
Formula C14H28ClN3O10 M.Wt 433.84
Solubility Water: 25 mg/mL (57.62 mM); DMSO: 1.67 mg/mL (3.85 mM; ultrasonic and warming and heat to 80°C) Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Kasugamycin hydrochloride hydrate

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 2.305 mL 11.525 mL 23.05 mL
5 mM 461 μL 2.305 mL 4.61 mL
10 mM 230.5 μL 1.1525 mL 2.305 mL
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**When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / CoA (available online).

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In vivo Formulation Calculator (Clear solution) of Kasugamycin hydrochloride hydrate

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % saline
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

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Reviews

Review for Kasugamycin hydrochloride hydrate

Average Rating: 5 ★★★★★ (Based on Reviews and 17 reference(s) in Google Scholar.)

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