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LXW7

Catalog No.GC36500

LXW7, a cyclic peptide containing Arg-Gly-Asp (RGD), is an integrin αvβ3 inhibitor.

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LXW7 Chemical Structure

Cas No.: 1313004-77-1

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

LXW7 is an octamer disulfide cyclic peptide, also a αvβ3 integrin ligand, acts as a potent and specific endothelial progenitor cells (EPCs) and endothelial cells (ECs) targeting ligand. LXW7 increases phosphorylation of VEGFR-2 and activation of ERK1/2[1]. αvβ3[1]

[1]. Hao D, et al. Discovery and Characterization of a Potent and Specific Peptide Ligand Targeting Endothelial Progenitor Cells and Endothelial Cells for Tissue Regeneration. ACS Chem Biol. 2017 Apr 21;12(4):1075-1086.

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