Mcl1-IN-12 |
| Catalog No.GC36558 |
Mcl1-IN-12 (Compound F) is a selective Mcl-1 inhibitor, less potent at Bcl-2, with Kis of 0.29 and 3.1 μM, respectively. Anti-tumor activity.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2042211-12-9
Sample solution is provided at 25 µL, 10mM.
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Mcl1-IN-12 (Compound F) is a selective Mcl-1 inhibitor, less potent at Bcl-2, with Kis of 0.29 and 3.1 μM, respectively. Anti-tumor activity[1]. Ki: 0.29 (Mcl-1), 3.1 μM (Bcl-2)[1]
[1]. Wang M, et al. Design, synthesis, and activity evaluation of selective inhibitors of anti-apoptotic Bcl-2 proteins: The effects on the selectivity of the P1 pockets in the active sites. Bioorg Med Chem Lett. 2016 Nov 1;26(21):5207-5211.
Average Rating: 5 (Based on Reviews and 33 reference(s) in Google Scholar.)
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