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Oleanolic acid derivative 2 Catalog No.GC36796

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1mg
$93.00
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5mg
$324.00
In stock

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Sample solution is provided at 25 µL, 10mM.

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Chemical Properties

Cas No. 211516-63-1 SDF Download SDF
Synonyms N/A
Chemical Name N/A
Canonical SMILES C[C@@]12CC[C@](C(CC3)=O)([H])[C@@]3(C)[C@@]1([H])CC=C4[C@]5([H])CC(C)(C)CC[C@@](C(OC)=O)5CC[C@@]24C
Formula C28H42O3 M.Wt 426.63
Solubility Soluble in DMSO Storage Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
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Background

Oleanolic acid derivative 2 is an oleanolic acid derivative, which is a novel triterpenoid-steroid hybrid molecule.

Oleanolic acid suppress transcription or translation of inducible nitric oxide synthase (iNOS) and inducible cyclooxygenase (COX-2) genes. extracted from the reference, compound 12a. For the transformation of olefin 9a into ketone 12a , the obvious ozonolysis cannot be used because ozone also reacts with the C-12 olefin of oleanane triterpenoids to give the 12R,13R-epoxide, 12-ketone,9 and 12R-hydroxy lactone.[1].

[1]. Tadashi Honda, et al. Design and Synthesis of 23,24-Dinoroleanolic Acid Derivatives, Novel Triterpenoid-Steroid Hybrid Molecules. J. Org. Chem., 1998, 63 (14), pp 4846-4849.