VU6001376 |
| Catalog No.GC37931 |
VU6001376 is a potent and selective positive allosteric modulator of the metabotropic glutamate receptor 4 (mGlu4 PAM) with an EC50 of 50.1 nM.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1968546-34-0
Sample solution is provided at 25 µL, 10mM.
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VU6001376 is a potent and selective positive allosteric modulator of the metabotropic glutamate receptor 4 (mGlu4 PAM) with an EC50 of 50.1 nM[1]. mGlu4|50.1 nM (EC50)
[1]. Bollinger SR, et al. Discovery, Structure-Activity Relationship, and Biological Characterization of a Novel Series of 6-((1 H-Pyrazolo[4,3- b]pyridin-3-yl)amino)-benzo[ d]isothiazole-3-carboxamides as Positive Allosteric Modulators of the Metabotropic Glutamate Receptor 4 (mGlu4). J Med Chem. 2019 Jan 10;62(1):342-358.
Average Rating: 5 (Based on Reviews and 7 reference(s) in Google Scholar.)
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