NS3623 |
| Catalog No.GC38471 |
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 343630-41-1
Sample solution is provided at 25 µL, 10mM.
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NS3623 is a hERG (KV11.1) and KV4.3 channel activator. NS3623 activates the IKr and Ito currents and has antiarrhythmic effect[1][2].
[1]. Hansen RS, et al. In vivo effects of the IKr agonist NS3623 on cardiac electrophysiology of the guinea pig. J Cardiovasc Pharmacol. 2008 Jul;52(1):35-41. [2]. Diness JG, et al. Antiarrhythmic effect of IKr activation in a cellular model of LQT3. Heart Rhythm. 2009 Jan;6(1):100-6. [3]. Calloe K, et al. A dual potassium channel activator improves repolarization reserve and normalizes ventricular action potentials. Biochem Pharmacol. 2016 May 15;108:36-46.
Average Rating: 5 (Based on Reviews and 21 reference(s) in Google Scholar.)
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