AF40431 |
| Catalog No.GC38586 |
AF40431, the first reported small-molecule ligand of sortilin, has an IC50 of 4.4 ?M and a Kd of 0.7 ?M .
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Cas No.: 181125-92-8
Sample solution is provided at 25 µL, 10mM.
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AF40431, the first reported small-molecule ligand of sortilin, has an IC50 of 4.4 µM and a Kd of 0.7 µM . AF40431 is bound in the neurotensin-binding site of sortilin[1].
[1]. Andersen JL, et al. Identification of the first small-molecule ligand of the neuronal receptor sortilin and structure determination of the receptor-ligand complex. Acta Crystallogr D Biol Crystallogr. 2014 Feb;70(Pt 2):451-60.
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