Home>>4-Methylethcathinone metabolite (hydrochloride) ((±)-Pseudoephedrine stereochemistry)

4-Methylethcathinone metabolite (hydrochloride) ((±)-Pseudoephedrine stereochemistry) (Synonyms: 4MEC metabolite, 4methylNethyl Cathinone metabolite)

Catalog No.GC45350

 

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4-Methylethcathinone metabolite (hydrochloride) ((±)-Pseudoephedrine stereochemistry) Chemical Structure

Size Price Stock Qty
500μg
$128.00
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1mg
$194.00
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5mg
$899.00
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Sample solution is provided at 25 µL, 10mM.

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Quality Control & SDS

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Background

4-methylethcathinone (4-MEC) (hydrochloride) is a cathinone derivative identified in several designer, recreational drugs that are sold as "legal high" replacements for controlled stimulants such as methamphetamine and 3,4-methylenedioxymethamphetamine.1,2,3 This metabolite of 4-MEC features conversion of the β-keto group to β-hydroxy and is an enantiomeric mixture of the R,R and S,S orientations at carbons one and two, as in pseudoephedrine. The physiological and toxicological properties of this compound have not been elucidated. This product is intended for research and forensic applications.

References
1. Schifano, F., Albanese, A., Fergus, S., et al. Mephedrone (4-methylmethcathinone; 'meow meow'): Chemical, pharmacological and clinical issues. Psychoparmacol.(Berl). 214(3), 593-602 (2011).
2. Santali, E.Y., Cadogan, A.K., Nic Daeid, N., et al. Synthesis, full chemical characterisation and development of validated methods for the quantification of (±)-4'-methylmethcathinone (mephedrone): A new "legal high". Journal of Pharmaceutical & Biomedical Analysis 56, 246-255 (2011).
3. Gibbons, S., and Zloh, M. An analysis of the 'legal high' mephedrone. Bioorg. Med. Chem. Lett. 20(14), 4135-4139 (2010).

Chemical Properties

Cas No. SDF
Synonyms 4MEC metabolite, 4methylNethyl Cathinone metabolite
Canonical SMILES C[C@@H](NCC)[C@H](O)C1=CC=C(C)C=C1.Cl
Formula C12H19NO.HCl M.Wt 229.8
Solubility DMF: 50mg/ml,DMSO: 50mg/ml,Ethanol: 30mg/ml,PBS (pH 7.2): 10mg/ml Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

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1 mg 5 mg 10 mg
1 mM 4.3516 mL 21.7581 mL 43.5161 mL
5 mM 0.8703 mL 4.3516 mL 8.7032 mL
10 mM 0.4352 mL 2.1758 mL 4.3516 mL
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
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