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2'-O-Methyladenosine-5'-Triphosphate

Catalog No.GN20008

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2'-O-Methyladenosine-5'-Triphosphate Chemical Structure

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1µmole
$66.00
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5µmole
$270.00
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10µmole
$503.00
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Sample solution is provided at 25 µL, 10mM.

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Description

2'-O-Methyladenosine-5'-Triphosphate is an ATP analog which is methylated at the 2'-O position of the ribose sugar. Methylation at this position results in increased stability of the resulting RNA strand against base hydrolysis and nuclease cleavage. This makes it a useful NTP for aptamer synthesis where increased variation in nucleotide composition along with increased nuclease resistance are desired.

Product Details

purity >95.00% Extinction Coefficient 15,400 Lmol-1cm-1 at 258 nm
Formula C11H18N5O13P3 (free acid) M.Wt 521.20 g/mole (free acid)
Salt Form Li+ Concentration 100 mM
Buffer H2O Storage -20°C or below
Synonyms 2'-O-Methyl-ATP Backbone 5'-Triphosphate
Base Analog Adenosine Sugar Type 2'-O-Methyl
Nucleotide Category Sugar Modified
Applications Aptamers, Epigenetics/DNA Damage

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