Heptaminol |
| Catalog No.GC47423 |
An aliphatic amine with cardiotonic and sympathomimetic activities
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 372-66-7
Sample solution is provided at 25 µL, 10mM.
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Heptaminol is an aliphatic amine with cardiotonic and sympathomimetic activities.1,2,3 It decreases the amplitude of peak calcium currents by 30% in isolated guinea pig ventricular myocytes when used at a concentration of 100 µM.1 Heptaminol inhibits norepinephrine uptake and induces catecholamine release in primary bovine chromaffin cells.3,2 It increases blood pressure in cats when administered intravenously at a dose of 15 mg, an effect that can be blocked by reserpine .4
1.Peineau, N., Mongo, K.G., Le Guennec, J.-Y., et al.Alteration of the L-type calcium current in guinea-pig single ventricular myocytes by heptaminol hydrochlorideBr. J. Pharmacol.107(1)104-108(1992) 2.Grobecker, H.On the mode of action of heptaminolNaunyn Schmiedebergs Arch Pharmakol.266(4)339-340(1970) 3.Delicado, E.G., Fideu, M.D., Miras-Portugal, M.T., et al.Effect of tuamine, heptaminol and two analogues on uptake and release of catecholamines in cultured chromaffin cellsBiochem. Pharmacol.40(4)821-825(1990) 4.Garrett, J., Osswald, W., and Goncalves Moriera, M.Mechanism of cardiovascular actions of heptanolaminesBr. J. Pharmacol. Chemother.18(1)49-60(1962)
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