ICA 110381 |
| Catalog No.GC10560 |
KV7.2/7.3 activator
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 325457-99-6
Sample solution is provided at 25 µL, 10mM.
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ICA 110381 (Compound 16) is a KCNQ2/Q3 potassium channel opener for the treatment of epilepsy. ICA 110381 is a KCNQ2/Q3 agonist (EC50=0.38 μM) as well as KCNQ1 antagonist (IC50=15 μM)[1].
References:
[1]. Amato G, et al. N-Pyridyl and Pyrimidine Benzamides as KCNQ2/Q3 Potassium Channel Openers for the Treatment of Epilepsy. ACS Med Chem Lett. 2011 Mar 31;2(6):481-4.
Review for ICA 110381
Average Rating: 5 (Based on Reviews and 38 reference(s) in Google Scholar.)
Review for ICA 110381
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