Indo-1 AM (Indo-1 Acetoxymethyl ester) (Synonyms: Indo-1 Acetoxymethyl ester) |
| Catalog No.GC33592 |
Indo-1 AM (Indo-1 Acetoxymethyl ester) is a fluorescent Ca2+ indicator (Λex=340 nm, Λem=405/485 nm).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 112926-02-0
Sample solution is provided at 25 µL, 10mM.
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Indo-1 AM is a fluorescent Ca2+ indicator (λex=340 nm, λem=405/485 nm).
Indo-1 AM is a fluorescent Ca2+ indicator with λex=340 nm and λem=405/485 nm[1]. In rabbit hearts that are exposed to Indo-1 AM, 72% of the dye is in the cytosol, and the remainder is associated with the mitochondria, microsomes and the nucleus[2].
[1]. Andrienko T, et al. Real-Time Fluorescence Measurements of ROS and [Ca2+] in Ischemic / Reperfused Rat Hearts: Detectable Increases Occur only after Mitochondrial Pore Opening and Are Attenuated by Ischemic Preconditioning. PLoS One. 2016 Dec 1;11(12):e0167300. [2]. Blatter LA, et al. Intracellular diffusion, binding, and compartmentalization of the fluorescent calcium indicators indo-1 and fura-2. Biophys J. 1990 Dec;58(6):1491-9.
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