Isoastragaloside I (Isoastragaloside-I) |
| Catalog No.GC33783 |
Isoastragaloside I (Isoastragaloside-I) is a natural compound from the medicinal herb Radix Astragali; possesses the activity of elevating adiponectin production.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 84676-88-0
Sample solution is provided at 25 µL, 10mM.
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Isoastragaloside I is a natural compound from the medicinal herb Radix Astragali; possesses the activity of elevating adiponectin production.IC50 value:Target:Astragaloside II and isoastragaloside I selectively increased adiponectin secretion in primary adipocytes without any obvious effects on a panel of other adipokines. Furthermore, an additive effect on induction of adiponectin production was observed between these two compounds and rosiglitazone, a thiazolidinedione class of insulin-sensitizing drugs. Chronic administration of astragaloside II and isoastragaloside I in both dietary and genetic obese mice significantly elevated serum levels of total adiponectin and selectively increased the composition of its high molecular weight oligomeric complex.
[1]. Xu A, et al. Selective elevation of adiponectin production by the natural compounds derived from a medicinal herb alleviates insulin resistance and glucose intolerance in obese mice. Endocrinology. 2009 Feb;150(2):625-33.
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