Lubiprostone (Synonyms: RU0211, SPI0211) |
| Catalog No.GC16890 |
activator of ClC-2 chloride channels
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 136790-76-6
Sample solution is provided at 25 µL, 10mM.
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Lubiprostone(SPI-0211;RU0211) is a gastrointestinal agent used for the treatment of idiopathic chronic constipation.Target: OthersLubiprostone is a bicyclic fatty acid derived from prostaglandin E1 that acts by specifically activating ClC-2 chloride channels on the apical aspect of gastrointestinal epithelial cells, producing a chloride-rich fluid secretion. These secretions soften the stool, increase motility, and promote spontaneous bowel movements (SBM). From Wikipedia.
References:
[1]. http://en.wikipedia.org/wiki/Lubiprostone
Average Rating: 5 (Based on Reviews and 17 reference(s) in Google Scholar.)
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