Luteoloside (Synonyms: Cynaroside, Luteolin 7-β-D-Glucopyranoside, Luteolin 7-O-Glucoside) |
| Catalog No.GC41452 |
Luteoloside is a flavonoid that has been found in many Chinese herbs with diverse biological activities.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 5373-11-5
Sample solution is provided at 25 µL, 10mM.
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Luteoloside is a flavonoid that has been found in many Chinese herbs with diverse biological activities. It reduces lactate dehydrogenase (LDH) and caspase-3 activities and production of reactive oxygen species (ROS) and increases cell viability and 14-3-3η protein levels in H9C2 cardiomyocytes after anoxia/reoxygenation injury. Luteoloside blocks 3C protease activity (IC50 = 0.36 mM) and reduces the cytopathic effect of enterovirus 71 in rhabdomyosarcoma cells (EC50 = 0.43 mM). It inhibits the growth of hepatocellular carcinoma (HCC) cells in vitro via reduction in ROS accumulation, caspase-1 activity, and expression of the NLRP3 inflammasome and reduces the number of lung metastases in an SMMC-7721 HCC mouse xenograft model when administered at a dose of 2 mg/kg. Luteoloside also reduces acanthosis and expression of epidermal differentiation markers in a mouse model of psoriasis induced by imiquimod .
Average Rating: 5 (Based on Reviews and 19 reference(s) in Google Scholar.)
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