Malformin C (Synonyms: Malformin B1b) |
| Catalog No.GC41186 |
Malformin C is a natural fungus-derived bicyclic pentapeptide that has antibacterial properties, particularly against species of Bacillus.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 59926-78-2
Sample solution is provided at 25 µL, 10mM.
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Malformin C is a natural fungus-derived bicyclic pentapeptide that has antibacterial properties, particularly against species of Bacillus. Malformin C potently blocks the ability of bleomycin to induce G2 arrest in human T-cell leukemia-derived Jurkat cells (IC50 = 0.9 nM). It less potently abrogates colchicine-induced M phase arrest in Jurkat cells (IC50 = 24 nM). Malformin C inhibits cell growth dose-dependently in Colon 38 and HCT 115 cancer cells (IC50s = 0.27 and 0.18 µM, respectively) but has a low therapeutic index against cancer xenografts when tested in mice.
Average Rating: 5 (Based on Reviews and 33 reference(s) in Google Scholar.)
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