Methiocarb (Synonyms: Mercaptodimethur, 4-Methylthio-3,5-dimethylphenyl methylcarbamate, BAY 37344) |
Catalog No.GC47646 |
A carbamate pesticide
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2032-65-7
Sample solution is provided at 25 µL, 10mM.
Quality Control & SDS
- View current batch:
- Purity: >98.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Methiocarb is a carbamate pesticide with insecticidal, molluscicidal, acaricidal, and bird repellant properties.1,2,3,4,5 It inhibits acetylcholinesterase (AChE) activity and is toxic to the western flower thrip (F. occidentalis; IC50 = 2.1 μM; LC50 = 3.26 ppm).2 Methiocarb is also toxic to the land snail M. obstructa (LD50 = 27.4 μg/snail) and the citrus mite A. pelekassi, inducing 94% mortality when used at a concentration of 0.5 ppm.1,3 It reduces the seasonal percentages of cotton bolls infested with pink bollworm (P. gossypiella) to 4%, compared with 65% infestation in untreated controls, when applied to cotton fields at a concentration of 1.86 lb/acre.5 Methiocarb reduces damage to grapes by song birds when applied to vineyards at a concentration of 2.5 lbs AI per 100 gal water per acre.4 It is an estrogen receptor α (ERα) and ERβ agonist (EC20s = 19.87 and 20.24 μM, respectively) and an androgen receptor antagonist (IC50 = 13.89 μM) in cell-based reporter assays.6 It is toxic to juvenile rainbow trout (O. mykiss) and guppies (P. reticulata) with LC50 values of 0.8 and 1.48 mg/L, respectively, at 48 hours of exposure.7 Formulations containing methiocarb have been used in the agricultural control of pests.
1.Hussein, H.I., Al-Rajhy, D., El-Shahawi, F.I., et al.Molluscicidal activity of Pergularia tomentosa (L.), methomyl and methiocarb, against land snailsInt. J. Pest Mgt.45(3)211-213(2010) 2.Jensen, S.E.Acetylcholinesterase activity associated with methiocarb resistance in a strain of western flower thrips, Frankliniella occidentalis (Pergande)Pesicide Biochem. Physiol.61(3)191-200(1998) 3.Reed, D.K., Crittenden, C.R., and Lyon, D.J.Acaricides screened against two rust mites of citrusJ. Econ. Entomol.60(3)668-671(1967) 4.Kassa, H., and Jackson, W.B.Mesurol as a bird repellent on grapes in OhioBird Control Seminars Proceedings(1979) 5.McGarr, R.L., Chapman, A.J., and Martin, D.F.Field tests with several insecticides for control of the pink bollworm, boll weevil, and bollwormJ. Econ. Entomol58(4)693-694(1965) 6.Tange, S., Fujimoto, N., Uramaru, N., et al.In vitro metabolism of methiocarb and carbaryl in rats, and its effect on their estrogenic and antiandrogenic activitiesEnviron. Toxicol. Pharmacol.41289-297(2016) 7.Boran, M., Altinok, I., and Capkin, E.Acute toxicity of carbaryl, methiocarb, and carbosulfan to the rainbow trout (Oncorhynchus mykiss) and guppy (Poecilia reticulata)Turk. J. Vet. Animal Sci.31(1)39-45(2007)
Cas No. | 2032-65-7 | SDF | |
Synonyms | Mercaptodimethur, 4-Methylthio-3,5-dimethylphenyl methylcarbamate, BAY 37344 | ||
Canonical SMILES | O=C(NC)OC1=CC(C)=C(SC)C(C)=C1 | ||
Formula | C11H15NO2S | M.Wt | 225.3 |
Solubility | DMF: 20 mg/ml,DMSO: 20 mg/ml,DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml,Ethanol: 10 mg/ml | Storage | Store at -20°C |
General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
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Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. |
Prepare stock solution | |||
1 mg | 5 mg | 10 mg | |
1 mM | 4.4385 mL | 22.1926 mL | 44.3853 mL |
5 mM | 0.8877 mL | 4.4385 mL | 8.8771 mL |
10 mM | 0.4439 mL | 2.2193 mL | 4.4385 mL |
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Average Rating: 5
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