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ω-Conotoxin GVIA TFA

Catalog No.GC62067

Products are for research use only. Not for human use. We do not sell to patients.

ω-Conotoxin GVIA TFA Chemical Structure

Size Price Stock Qty
1 mg
$495.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Description of ω-Conotoxin GVIA TFA

ω-Conotoxin GVIA TFA is an inhibitor of the N-type Ca2+ channel[1].

ω-conotoxin GVIA (50 nM, 50 nL) inhibits the effects of urotensin II (UII)[1].

[1]. Ya-Kun Cao, et al. Microinjection of urotensin II into the rostral ventrolateral medulla increases sympathetic vasomotor tone via the GPR14/ERK pathway in rats. Hypertens Res. 2020 Aug;43(8):765-771.

Chemical Properties of ω-Conotoxin GVIA TFA

Cas No. SDF
Formula C120H182N38O43S6.C2HF3O2 M.Wt 3151.37
Solubility Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of ω-Conotoxin GVIA TFA

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 0.3173 mL 1.5866 mL 3.1732 mL
5 mM 0.0635 mL 0.3173 mL 0.6346 mL
10 mM 0.0317 mL 0.1587 mL 0.3173 mL
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**When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / CoA (available online).

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In vivo Formulation Calculator (Clear solution) of ω-Conotoxin GVIA TFA

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

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Reviews

Review for ω-Conotoxin GVIA TFA

Average Rating: 5 ★★★★★ (Based on Reviews and 12 reference(s) in Google Scholar.)

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