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PCL 016

Catalog No.GC32372

PCL 016 is a topical antiviral agent, which inhibits adenovirus replication in rabbit.

Products are for research use only. Not for human use. We do not sell to patients.

PCL 016 Chemical Structure

Cas No.: 98-98-6

Size Price Stock Qty
10mM (in 1mL DMSO)
$50.00
In stock
5g
$46.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Description Protocol Chemical Properties Product Documents Related Products

PCL 016 is a topical antiviral agent, which inhibits adenovirus replication in rabbit.

Topical 1.5% PCL, 0.8% PCL, 0.369% PCL (pH7), 0.369% PCL (pH4) and 0.5% CDV are significantly more effective than the Control in reducing Ad Positive Cultures/Total (Days 1-14) and the Duration of Ad Shedding in the Ad5/NZW rabbit ocular model. Although not statistically significant, there appears to be a trend toward concentration-dependent efficacy of PCL 016 on the Duration of Ad Shedding. There is no apparent ocular toxicity associated with PCL 016 concentrations[1].

[1]. E.G. Romanowski, et al. A Novel Topical Antiviral Agent, PCL-016 (Picolinic Acid), Inhibits Adenovirus Replication in the Ad5/NZW Rabbit Ocular Model. ARVO Annual Meeting Abstract. May 2005 Volume 46, Issue 13.

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