PCL 016 |
Catalog No.GC32372 |
PCL 016 is a topical antiviral agent, which inhibits adenovirus replication in rabbit.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 98-98-6
Sample solution is provided at 25 µL, 10mM.
PCL 016 is a topical antiviral agent, which inhibits adenovirus replication in rabbit.
Topical 1.5% PCL, 0.8% PCL, 0.369% PCL (pH7), 0.369% PCL (pH4) and 0.5% CDV are significantly more effective than the Control in reducing Ad Positive Cultures/Total (Days 1-14) and the Duration of Ad Shedding in the Ad5/NZW rabbit ocular model. Although not statistically significant, there appears to be a trend toward concentration-dependent efficacy of PCL 016 on the Duration of Ad Shedding. There is no apparent ocular toxicity associated with PCL 016 concentrations[1].
[1]. E.G. Romanowski, et al. A Novel Topical Antiviral Agent, PCL-016 (Picolinic Acid), Inhibits Adenovirus Replication in the Ad5/NZW Rabbit Ocular Model. ARVO Annual Meeting Abstract. May 2005 Volume 46, Issue 13.
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