Pentadecanoyl-L-carnitine (chloride) (Synonyms: CAR 15:0, C15:0 Carnitine, L-Carnitine pentadecanoyl ester, L-Pentadecanoylcarnitine) |
| Catalog No.GC52306 |
A CB receptor agonist
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 173686-57-2
Sample solution is provided at 25 µL, 10mM.
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Pentadecanoyl-L-carnitine is a cannabinoid (CB) receptor agonist (EC50s = 3.7 and 3.2 µM for CB1 and CB2 receptors, respectively, in a cAMP modulation assay).1 It is also an agonist at the serotonin (5-HT) receptor subtypes 5-HT1A and 5-HT1B (EC50s = 9.6 and 9.3 µM, respectively) and an antagonist at histamine H1 and H2 receptors (EC50s = 10.9 and 6.1 µM, respectively). Pentadecanoyl-L-carnitine inhibits T cell proliferation in an SAg primary human cell system and reduces chemokine (C-C) motif ligand 2 (CCL2) levels in an Mphg primary human cell system.
1.Venn-Watson, S., Reiner, J., and Jensen, E.D.Pentadecanoylcarnitine is a newly discovered endocannabinoid with pleiotropic activities relevant to supporting physical and mental healthSci. Rep.12(1)13717(2022)
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