PSB-1584 |
| Catalog No.: GB40333 |
GPR84 is an orphan G protein-coupled receptor that is activated by medium-chain fatty acids and hydroxy fatty acids although these may not be its endogenous agonist.
Sample solution is provided at 25 µL, 10mM.
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Quality Control & SDS
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Purity: >98.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
GPR84 is an orphan G protein-coupled receptor that is activated by medium-chain fatty acids and hydroxy fatty acids although these may not be its endogenous agonist. It is highly expressed on immune cells and expression levels rise after exposure to inflammatory stimuli. Potent synthetic agonists enhance proinflammatory signaling and macrophage effector functions. PSB-1584 is a potent synthetic exogenous agonist at GPR84, EC50=5 nM which is selective against other free fatty acid receptors and is metabolically stable when incubated with human liver microsomes. An important new tool for studying the physiology of GPR84.
| Cas No. | 72255-76-6 | SDF | Download SDF |
| Formula | 211.26 | M.Wt | C10H17N3O2 |
| Solubility | Storage | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. | ||
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
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