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Home >> Signaling Pathways >> Neuroscience >> Gap Junction

Gap Junction

Gap junctions are bunch of intercellular channels that allows transfer of ions and small through neighbouring cells. It is involved in regeneration, development and homeostasis regulation.

Products for  Gap Junction

  1. Cat.No. Product Name Information
  2. GC13863 10Panx

    10Panx

     10Panx is a potent Panx1 channel inhibitor that targets the W74 to Y83 segment of the ECL1 of Panx1 protein. 10Panx Chemical Structure
  3. GC31538 AT-1002

    AT-1002, a 6-mer synthetic peptide, is a tight junction regulator and absorption enhancer.

     AT-1002 Chemical Structure
  4. GC34477 AT-1002 TFA AT-1002 TFA is a six-mer synthetic peptide that decreases transepithelial electrical resistance (TEER). AT-1002 TFA Chemical Structure
  5. GC10624 Carbenoxolone disodium Carbenoxolone disodium is a semi-synthetic derivative of glycyrrhetinic acid, an orally active gap junction/hemichannel inhibitor and a non-selective inhibitor of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1). Carbenoxolone disodium Chemical Structure
  6. GC79130 Cx43 HC-IN-1 Cx43 HC-IN-1 (Compound D4) is a selective and orally active inhibitor of connexin hemichannels ( Cx43 HC ). Cx43 HC-IN-1 Chemical Structure
  7. GC35806 Danegaptide Danegaptide is a potent, selective, and orally active gap-junction modifier. Danegaptide Chemical Structure
  8. GC35807 Danegaptide Hydrochloride Danegaptide Hydrochloride is a potent, selective, and orally active gap-junction modifier. Danegaptide Hydrochloride Chemical Structure
  9. GC60866 Gap 26 TFA Gap 26 TFA is a connexin mimetic peptide, composed of residue numbers 63-75 of the first extracellular loop of connexin 43 (gap junction blocker), containing the SHVR amino acid motif. Gap 26 TFA Chemical Structure
  10. GP10119 Gap 27

    Ser-Arg-Pro-Thr-Glu-Lys-Thr-Ile-Phe-Ile-Ile

    Gap 27 is a peptide (Ser-Arg-Pro-Thr-Glu-Lys-Thr-Ile-Phe-Ile-Ile) derived from connexin43 (Cx43) and is a selective gap junction blocker. Gap 27 Chemical Structure
  11. GC17681 Gap19 Gap19 is a Cx43 hemichannel blocker derived from the second cytoplasmic loop of Cx43. Gap19 Chemical Structure
  12. GC33822 Larazotide acetate Larazotide acetate is an eight-amino acid peptide, exhibiting antiviral activity with EC50 values of 44.14µM and 59.06µM for varicella-zoster virus strains OKA and 07-1, respectively. Larazotide acetate Chemical Structure
  13. GC38657 Meclofenamate sodium

    Meclofenamic Acid

     Meclofenamic acid (Meclofenamate) sodium is a nonsteroidal anti-inflammatory drug (NSAID) approved for use in arthritis (osteo and rheumatoid), analgesia (mild to moderate pain), dysmenorrhea, and heavy menstrual blood loss (menorrhagia). Meclofenamate sodium Chemical Structure
  14. GC11058 Scrambled 10Panx

    Scrambled 10Panx Phe-Ser-Val-Tyr-Trp-Ala-Gln-Ala-Asp-Arg

    Panx-1 mimetic inhibitory peptide, blocks pannexin-1 gap junctions

     Scrambled 10Panx Chemical Structure
  15. GC12096 Semagacestat (LY450139)

    LY450139

     A pan γ-secretase inhibitor Semagacestat (LY450139) Chemical Structure
  16. GC62257 TAT-Gap19 TFA TAT-Gap19 TFA is a Cx mimetic peptide and a specific inhibitor of connexin 43 (Cx43) hemichannels (HCs). TAT-Gap19 TFA Chemical Structure
  17. GC16494 Tonabersat

    SB-220453

     An anti-migraine agent Tonabersat Chemical Structure

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