URAT1
URAT1, also known as SLC22A12, is an organic anion and urate transporter. It regulates urate levels of blood and is required for urate reabsorption of kidney.
Products for URAT1
- Cat.No. Product Name Information
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GC15440
Lesinurad
A URAT1 inhibitor
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GC36439
Lesinurad sodium
RDEA-594 sodium
Lesinurad sodium is a URAT1 and OAT inhibitor, is determined to be a substrate for the kidney transporters OAT1 and OAT3 with Km values of 0.85 and 2 ?M, respectively. -
GC69779
Puliginurad
YL-90148
Puliginurad (YL-90148) is an effective inhibitor of urate transporter protein (URAT). Puliginurad can be used in research on hyperuricemia and gout.
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GC63422
Ruzinurad
HR011303; SHR4640
Ruzinurad is a highly selective URATl inhibitor (WO2020088641, compound I). -
GC65362
URAT1 inhibitor 1
URAT1 inhibitor 1 (1g) is a uric acid transporter 1 (URAT1) inhibitor, with an IC50 of 32 nM.
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GC71155
URAT1 inhibitor 3
URAT1 inhibitor 3 is a potent, orally active, selective URAT1 inhibitor with an IC50 value of 0.8 nM.
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GC71286
URAT1 inhibitor 6
URAT1 inhibitor 6 (Compound 1h) is a potent URAT1 inhibitor (IC50: 35 nM for hURAT1).
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GC71287
URAT1 inhibitor 8
URAT1 inhibitor 8 (example 247) is a potent URAT1 inhibitor, with an IC50 of 0.001 μM.
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GC71285
URAT1&XO inhibitor 1
URAT1&XO inhibitor 1 (compound 29) is a dual inhibitor of both URAT1 (IC50=~10 μM) and Xanthine Oxidase (IC50=1.01 μM).
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GC71288
URAT1&XO inhibitor 2
URAT1&XO inhibitor 2 (Compound BDEO) is a dual inhibitor of xanthine oxidase and URAT1, with IC50 of 3.3 μM for xanthine oxidase.
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GC19373
Verinurad
Verinurad is an urate transporter inhibitor with EC50 value of 0.05 uM.
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GC70152
Xininurad
XNW3009
Xininurad (XNW3009) is a urate transporter (URAT) inhibitor.