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URAT1

URAT1, also known as SLC22A12, is an organic anion and urate transporter. It regulates urate levels of blood and is required for urate reabsorption of kidney.

Products for  URAT1

  1. Cat.No. Product Name Information
  2. GC15440 Lesinurad A URAT1 inhibitor Lesinurad  Chemical Structure
  3. GC36439 Lesinurad sodium

    RDEA-594 sodium

    Lesinurad sodium is a URAT1 and OAT inhibitor, is determined to be a substrate for the kidney transporters OAT1 and OAT3 with Km values of 0.85 and 2 ?M, respectively. Lesinurad sodium  Chemical Structure
  4. GC69779 Puliginurad

    YL-90148

    Puliginurad (YL-90148) is an effective inhibitor of urate transporter protein (URAT). Puliginurad can be used in research on hyperuricemia and gout.

    Puliginurad  Chemical Structure
  5. GC63422 Ruzinurad

    HR011303; SHR4640

    Ruzinurad is a highly selective URATl inhibitor (WO2020088641, compound I). Ruzinurad  Chemical Structure
  6. GC65362 URAT1 inhibitor 1 URAT1 inhibitor 1 (1g) is a uric acid transporter 1 (URAT1) inhibitor, with an IC50 of 32 nM. URAT1 inhibitor 1  Chemical Structure
  7. GC71155 URAT1 inhibitor 3 URAT1 inhibitor 3 is a potent, orally active, selective URAT1 inhibitor with an IC50 value of 0.8 nM. URAT1 inhibitor 3  Chemical Structure
  8. GC71286 URAT1 inhibitor 6 URAT1 inhibitor 6 (Compound 1h) is a potent URAT1 inhibitor (IC50: 35 nM for hURAT1). URAT1 inhibitor 6  Chemical Structure
  9. GC71287 URAT1 inhibitor 8 URAT1 inhibitor 8 (example 247) is a potent URAT1 inhibitor, with an IC50 of 0.001 μM. URAT1 inhibitor 8  Chemical Structure
  10. GC71285 URAT1&XO inhibitor 1 URAT1&XO inhibitor 1 (compound 29) is a dual inhibitor of both URAT1 (IC50=~10 μM) and Xanthine Oxidase (IC50=1.01 μM). URAT1&XO inhibitor 1  Chemical Structure
  11. GC71288 URAT1&XO inhibitor 2 URAT1&XO inhibitor 2 (Compound BDEO) is a dual inhibitor of xanthine oxidase and URAT1, with IC50 of 3.3 μM for xanthine oxidase. URAT1&XO inhibitor 2  Chemical Structure
  12. GC19373 Verinurad Verinurad is an urate transporter inhibitor with EC50 value of 0.05 uM. Verinurad  Chemical Structure
  13. GC70152 Xininurad

    XNW3009

    Xininurad (XNW3009) is a urate transporter (URAT) inhibitor.

    Xininurad  Chemical Structure

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