SRI-41315 |
| Catalog No.GC69942 |
SRI-41315 induces long pauses at termination codons, inhibits premature termination codons (PTCs) associated with permanent and primary human bronchial epithelial cell cystic fibrosis, restores the expression and function of CFTR (cystic fibrosis transmembrane conductance regulator). SRI-41315 inhibits PTCs by reducing the abundance of the termination factor eRF1. SRI-41315 also enhances aminoglycoside-mediated readthrough, resulting in synergistic increases in CFTR activity.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1613509-49-1
Sample solution is provided at 25 µL, 10mM.
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Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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