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Tezampanel (Synonyms: LY 293558;LY293558;LY-293558)

Catalog No.GC10415 Copy One-Click Copy Product Info

AMPA receptor antagonist

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Tezampanel Chemical Structure

Cas No.: 154652-83-2

Size Price Stock Qty
25mg
$909.00
In stock
5g
$12,000.00
Ship Within 7 Days

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Customer Reviews

Based on customer reviews.

Sample solution is provided at 25 µL, 10mM.



Description of Tezampanel

Tezampanel (LY293558) is a drug which acts as an antagonist at the AMPA and kainate families of ionotropic glutamate receptors, with selectivity for the GluR5 subtype of the kainate receptor. It has neuroprotective and anticonvulsant effects.

Chemical Properties of Tezampanel

Cas No. 154652-83-2 SDF
Synonyms LY 293558;LY293558;LY-293558
Chemical Name (3S,4aR,6R,8aR)-6-[2-(2H-tetrazol-5-yl)ethyl]-1,2,3,4,4a,5,6,7,8,8a-decahydroisoquinoline-3-carboxylic acid
Canonical SMILES C1CC2CNC(CC2CC1CCC3=NNN=N3)C(=O)O
Formula C13H21N5O2 M.Wt 279.34
Solubility Soluble in DMSO Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Tezampanel

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1 mg 5 mg 10 mg
1 mM 3.5799 mL 17.8993 mL 35.7987 mL
5 mM 716 μL 3.5799 mL 7.1597 mL
10 mM 358 μL 1.7899 mL 3.5799 mL
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In vivo Formulation Calculator (Clear solution) of Tezampanel

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

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Reviews

Review for Tezampanel

Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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