TMA-DPH (Synonyms: N,N,N-Trimethyl-4-(6-phenyl-1,3,5-hexatrien-1-yl)phenylammonium (p-toluenesulfonate)) |
Catalog No.GC45058 |
TMA-DPH is a fluorescent probe used for measuring membrane fluidity in artificial and living membrane systems.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 115534-33-3
Sample solution is provided at 25 µL, 10mM.
TMA-DPH is a fluorescent probe used for measuring membrane fluidity in artificial and living membrane systems.[1],[2],[3],[4] The cylindrical shape of TMA-DPH confers high sensitivity to reorientation resulting from changes in surrounding lipids. TMA-DPH has excitation and emission maxima at 355 and 430 nm, respectively.
Reference:
[1]. Subramanian, V., Knight, J.S., Parelkar, S., et al. Design, synthesis, and biological evaluation of tetrazole analogs of cl-amidine as protein arginine deiminase inhibitors. Journal of Medicinal Chemistry 58(3), 1337-1344 (2015).
[2]. Illinger, D., and Kurhy, J.G. The kinetic aspects of intracellular fluorescence labeling with TMA-DPH support the maturation model for endocytosis in L929 cells. Journal of Cell Biology 125(4), 783-794 (1994).
[3]. Illinger, D., Duportail, G., Mely, Y., et al. A comparison of the fluorescence properties of TMA-DPH as a probe for plasma membrane and for endocytic membrane. Biochimica et Biophysica Acta 1239(1), 58-66 (1995).
[4]. Chazotte, B. Labeling the plasma membrane with TMA-DPH. Cold Spring Harb.Protoc. 2011(5), (2011).).
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