VH 032 amide-alkylC4-acid |
| Catalog No.GC50544 |
VHL ligand with alkyl linker and terminal acid for onward chemistry
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2172819-74-6
Sample solution is provided at 25 µL, 10mM.
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Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC® research and development; incorporates an E3 ligase ligand plus alkylC4 linker with terminal carboxylic acid ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was VH 032 - linker 5 PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.
Zengerle et al (2015) Selective small molecule induced degradation of the BET bromodomain protein BRD4. ACS Chem.Biol. 10 1770 PMID:26035625 |Salami et al (2017) Waste disposal-An attractive strategy for cancer therapy. Science 355 1163 PMID:28302825
Average Rating: 5 (Based on Reviews and 18 reference(s) in Google Scholar.)
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