| (±)-SDZ-201 106 Catalog No.GC41677 |
Sample solution is provided at 25 µL, 10mM.
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| Cas No. | 97730-95-5 | SDF | Download SDF |
| Synonyms | N/A | ||
| Chemical Name | N/A | ||
| Canonical SMILES | OC(COC1=CC=CC2=C1C=C(C#N)N2)CN(CC3)CCN3C(C4=CC=CC=C4)C5=CC=CC=C5 | ||
| Formula | C29H30N4O2 | M.Wt | 466.6 |
| Solubility | Soluble in DMSO | Storage | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. | ||
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
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(±)-SDZ-201 106 is a diphenylpiperazinylindole derivative that prolongs the open state of cardiac voltage-gated Na+ channels. It has been shown to increase net Na+ influx and the activity of reverse mode Na+/Ca2+ exchange, which leads to an increase in intracellular Ca2+, as well as to partially inhibit the Na+ pump in cardiac myocytes. (±)-SDZ-201 106 is also reported to act as an open-channel blocker of delayed-rectifier K+ channels in NG108-15 neuronal cells.