13,14-dihydro-15-keto Prostaglandin F2α-d4 (Synonyms: PGFMd4)

Name: 13,14-dihydro-15-keto Prostaglandin F2α-d4
Brand: GlpBio
SKU: GC46429
Availability: InStock
Rating: 5 (35 reviews)

Catalog No.GC46429

An internal standard for the quantification of 13,14dihydro15keto PGF_2α

Products are for research use only. Not for human use. We do not sell to patients.

13,14-dihydro-15-keto Prostaglandin F2α-d4 Chemical Structure

Cas No.: 42932-59-2

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50 μg	$106.00	In stock
100 μg	$202.00	In stock
500 μg	$850.00	In stock

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Sample solution is provided at 25 µL, 10mM.

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Description Chemical Properties Product Documents

Product Documents

Quality Control & SDS

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Purity: >99.00%

13,14-dihydro-15-keto Prostaglandin F_2α-d₄ (13,14-dihydro-15-keto PGF_2α-d₄) contains four deuterium atoms at the 3, 3', 4, and 4' positions. It is intended for use as an internal standard for the quantification of 13,14-dihydro-15-keto PGF_2α by GC- or LC-mass spectrometry. 13,14-dihydro-15-keto PGF_2α is the first prominent plasma metabolite of PGF_2α in the 15-hydroxy PGDH pathway.¹ Measurement of 13,14-dihydro-15-keto PGF_2α in plasma can be used as a marker of the in vivo production of PGF_2α.^1,2,3

1.Samuelsson, B., Goldyne, M., GranstrÖm, E., et al.Prostaglandins and thromboxanesAnnu. Rev. Biochem.47997-1029(1978) 2.Del Vecchio, R.P., Maxey, K.M., and Lewis, G.S.A quantitative solid-phase enzymeimmunoassay for 13,14-dihydro-15-keto-prostaglandin F2α in plasmaProstaglandins43(4)321-330(1992) 3.Meyer, H.H.D., Eisele, K., and Osaso, J.A biotin-streptavidin amplified enzyme immunoassay for 13,14-dihydro-15-keto-PGF2αProstaglandins38(3)375-383(1989)

Cas No.	42932-59-2	SDF
Synonyms	PGFMd4
Canonical SMILES	CCCCCC(CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1C/C=C\C([2H])([2H])C([2H])([2H])CC(O)=O)=O
Formula	C20H30D4O5	M.Wt	358.5
Solubility	DMF: 50 mg/ml,DMSO: 50 mg/ml,Ethanol: 50 mg/ml,PBS (pH 7.2): 5 mg/ml	Storage	Store at -20°C
General tips	Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition	Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

Prepare stock solution
		1 mg	5 mg	10 mg
	1 mM	2.7894 mL	13.947 mL	27.894 mL
	5 mM	0.5579 mL	2.7894 mL	5.5788 mL
	10 mM	0.2789 mL	1.3947 mL	2.7894 mL

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In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg

Average weight of animals: g

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO + % + % Tween 80 + % ddH₂O

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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Average Rating: 5 ★★★★★ (Based on Reviews and 35 reference(s) in Google Scholar.)

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13,14-dihydro-15-keto Prostaglandin F2α-d4 (Synonyms: PGFMd4)

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