15-keto Latanoprost (free acid) |
| Catalog No.GC40989 |
15-keto Latanoprost is a potential metabolite of latanoprost when administered to animals.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 369585-22-8
Sample solution is provided at 25 µL, 10mM.
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15-keto Latanoprost is a potential metabolite of latanoprost when administered to animals. 15-keto Latanoprost is also one of the common minor impurities found in commercial preparations of the bulk drug compound. Although much less potent that the parent compound latanoprost, 15-keto latanoprost still retains the ability to produce a small but measurable decrease (1 mm Hg) in the intraocular pressure of normal cynomolgus monkeys when administered at a dose of 1 µg/eye. 15-keto Latanoprost is also a miotic in the normal cat eye, causing an 8 mm Hg reduction in pupillary diameter at 5 µg/eye. Again, this is not as potent as many other F-type prostaglandins; for example, prostaglandin F2α will produce this degree of miosis at a dose of less than 1 µg/eye.
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