3',4',7-Trihydroxyisoflavone (Synonyms: 3'-hydroxy Daidzein, 3’,4’,7-THIF) |
| Catalog No.GC40618 |
3',4',7-Trihydroxyisoflavone, a major metabolite of Daidzein, is an ATP-competitive inhibitor of Cot (Tpl2/MAP3K8) and MKK4. 3',4',7-Trihydroxyisoflavone has anticancer, anti-angiogenic, chemoprotective, and free radical scavenging activities.
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Cas No.: 485-63-2
Sample solution is provided at 25 µL, 10mM.
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3',4',7-Trihydroxyisoflavone is a natural isoflavonoid that has antioxidant activity. It can be produced by the metabolism of daidzein or daidzin . 3',4',7-Trihydroxyisoflavone inhibits several signaling pathways in cells, including tyrosinase-mediated melanin formation (IC50 = 5.2 µM), casein kinase II-mediated phosphorylation of 60S acidic ribosomal P proteins, and cyclin-dependent, kinase-regulated cell proliferation.
Average Rating: 5 (Based on Reviews and 32 reference(s) in Google Scholar.)
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