4-hydroxy Alternariol (Synonyms: 4-hydroxy AOH, 4-OH AOH) |
| Catalog No.GC18858 |
4-hydroxy Alternariol is a metabolite of the mycotoxin alternariol formed through cytochrome P450 (CYP450) metabolism.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 959417-21-1
Sample solution is provided at 25 µL, 10mM.
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4-hydroxy Alternariol is a metabolite of the mycotoxin alternariol formed through cytochrome P450 (CYP450) metabolism. It increases reactive oxygen species (ROS) in KYSE510 human esophageal cells by 701% compared to control. 4-hydroxy Alternariol increases topoisomerase IIβ-DNA complexes by 208% compared to control in an ICE assay but does not induce DNA damage in KYSE510 cells. It completely inhibits topoisomerase IIα activity at a concentration of 25 uM under cell-free conditions.
Review for 4-hydroxy Alternariol
Average Rating: 5 (Based on Reviews and 13 reference(s) in Google Scholar.)
Review for 4-hydroxy Alternariol
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