Anticonvulsant agent 1 (Synonyms: 4-(2,2-Difluoroethenyl)-α-ethyl-2-oxo-1-pyrrolidineacetamide) |
| Catalog No.GC33745 |
Anticonvulsant agent 1 is an anticonvulsant agent extracted from patent WO2001062726A2, Compound 156.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 357336-17-5
Sample solution is provided at 25 µL, 10mM.
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Anticonvulsant agent 1 is an anticonvulsant agent extracted from patent WO2001062726A2, Compound 156.
The inhibition constant (Ki) of Anticonvulsant agent 1 (Compound 156) is determined in competitive binding experiments by measuring the binding of a single concentration of a radioactive ligand at equilibrium with various concentrations of the unlabeled test substance. The concentration of the test substance inhibiting 50 % of the specific binding of the radioligand is called the IC50. The equilibrium dissociation constant Ki is proportional to the IC50 and is calculated. Anticonvulsant agent 1 shows pKi values of 6.0 and greater[1]
[1]. Differding, Edmond, et al. 2-OXO-1-PYRROLIDINE DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES. WO2001062726A2
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