Bethanechol chloride (Synonyms: (±)-Bethanechol, Carbamyl-β-methylcholine chloride, NSC 30783) |
| Catalog No.GC14419 |
Muscarinic receptor agonist
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 590-63-6
Sample solution is provided at 25 µL, 10mM.
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Bethanechol Chloride (Carbamyl-β-methylcholine chloride) is a selective muscarinic receptor agonist without any effect on nicotinic receptors.Target: mAChRBethanechol Chloride (Carbamyl-β-methylcholine chloride) is a parasympathomimetic choline carbamate that selectively stimulates muscarinic receptors without any effect on nicotinic receptors. Unlike acetylcholine, Bethanechol Chloride (Carbamyl-β-methylcholine chloride) is not hydrolyzed by cholinesterase and will therefore have a long duration of action. Oral bethanechol significantly improves contraction pressures and bolus transit in the smooth muscle portion of the esophagus in patients with severe IEM [1]. Bethanechol Chloride (Carbamyl-β-methylcholine chloride) has potential benefit in the treatment of cerebral palsy [2].
References:
[1]. Agrawal, A., et al., Bethanechol improves smooth muscle function in patients with severe ineffective esophageal motility. J Clin Gastroenterol, 2007. 41(4): p. 366-70.
[2]. Carter, W.J., Unexpected benefits of bethanechol in adults with cerebral palsy. Med J Aust, 2008. 189(5): p. 293.
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