DA-3003-2 (Synonyms: NSC 663285) |
| Catalog No.GC41305 |
Cdc25 dual-specific protein tyrosine phosphatases are important for cell cycle progression and often overexpressed in cancers.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 383907-47-9
Sample solution is provided at 25 µL, 10mM.
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Cdc25 dual-specific protein tyrosine phosphatases are important for cell cycle progression and often overexpressed in cancers. Through the removal of inhibitory phosphates, they function to catalyze the activation of cyclin-Cdk complexes. DA-3003-2 is a Cdc25 phosphatase inhibitor (IC50 = 0.82 µM for human recombinant Cdc25B) that demonstrates antiproliferative activity. At 20 µM, it has been shown to arrest asynchronous PC-3 prostate cancer cells in G2/M phase.
Average Rating: 5 (Based on Reviews and 24 reference(s) in Google Scholar.)
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