Ec2la |
| Catalog No.GC50579 |
Ec2la is an orally active cannabinoid type-2 receptors (CB2Rs) positive allosteric modulator.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2244579-87-9
Sample solution is provided at 25 µL, 10mM.
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CB2 receptor positive allosteric modulator. Enhances CP 55940 and 2-Arachidonylglycerol -stimulated binding of [35S]GTPγS to CB2 receptors, but has no effect in the absence of agonist. Exhibits antinociceptive effects in an animal model of neuropathic pain.
Gado et al (2019) Identification of the first synthetic allosteric modulator of the CB2 receptors and evidence of its efficacy for neuropathic pain relief. J.Med.Chem. 62 276 PMID:29990428
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