Enterocin (Synonyms: Vulgamycin) |
Catalog No.GC10193
One-Click Copy Product Info
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antibiotic
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 59678-46-5
Sample solution is provided at 25 µL, 10mM.
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Enterocin is an antibiotic isolated from cultures of two strains of Streptomyces, Streptomyces candidus var. enterostaticus WS-8096 and variant M-127 of Streptomyces viridochromogenes. This antibiotic shows activity against Gram-positive and Gram-negative bacteria, especially against the Enterobacteriaceae [1]. Enterocin was named for its strong activity against Enterobacteriaceae.
The elementary analysis and mass spectroscopic measurement suggested that the molecular formula was C72H20O10. The ultraviolet absorption gave two maximal peaks at 250 nm and 283 nm in methanol [1]. The mechanism of enterocin is unknown. Enterocin acts synergistically with streptomycin and chloramphenicol. The genetics of enterocin biosynthesis has been extensively investigated. Enterocin is a small molecular weight secondary metabolite [1].
Reference:
[1] Miyairi N, SAKAI H E I I, KONOMI T, et al. Enterocin, a new antibiotic [J]. The Journal of antibiotics, 1976, 29(3): 227-235.
| Cas No. | 59678-46-5 | SDF | |
| Synonyms | Vulgamycin | ||
| Chemical Name | (3R,4aR,5S,6S,7S,7aS,8R)-7-benzoylhexahydro-4a,6,7a,8-tetrahydroxy-5-(4-methoxy-2-oxo-2H-pyran-6-yl)-3,6-methanocyclopenta[c]pyran-1(3H)-one | ||
| Canonical SMILES | O=C1[C@@]2(O)[C@@]([C@@H](C(O3)=CC(OC)=CC3=O)[C@]4(O)[C@@H]2C(C5=CC=CC=C5)=O)(O)C[C@@]([C@]([H])4O)([H])O1 | ||
| Formula | C22H20O10 | M.Wt | 444.4 |
| Solubility | DMSO: soluble,Ethanol: soluble,Methanol: soluble,Water: soluble | Storage | Store at -20°C |
| General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
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| Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. | ||
| Prepare stock solution | |||
|
1 mg | 5 mg | 10 mg |
| 1 mM | 2.2502 mL | 11.2511 mL | 22.5023 mL |
| 5 mM | 450 μL | 2.2502 mL | 4.5005 mL |
| 10 mM | 225 μL | 1.1251 mL | 2.2502 mL |
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
g
μL
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Quality Control & SDS
- View current batch:
- Purity: >98.00% Appearance: A solid
- COA (Certificate of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Average Rating: 5 (Based on Reviews and 7 reference(s) in Google Scholar.)